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Recent and rapid advances in technologies that permit large-scale creation and synthesis of longer pieces of synthetic DNA, as well as extremely fast, cheap and accurate sequencing of DNA, have changed the collective thinking about the feasible size and scope of projects. However, the high costs of sample preparation for high-throughput NGS have prevented labs from using these methods for routine processes like plasmid validation.
Check out a few blogs on how the plexWell™ technology enables Addgene to optimize the QC verification and validation of 1,000’s of plasmids per year.