ExpressPlex 2.0 Library Prep
Applications in Antibody Discovery, Development, & Manufacturing
Simplify prep. Sequence more. Accelerate antibody success.
ExpressPlex 2.0 library prep for insight-driven antibody decisions
ExpressPlex 2.0 reduces the time, effort, and cost of NGS library prep, enabling faster and more efficient progression from antibody discovery through engineering and production.
- TnX, next generation transposase: Reduced insertion bias and improved coverage uniformity
- Simple workflow: One-step fragmentation, barcoding, and amplification
- Auto-normalization & early sample pooling
- >80% labor and consumable costs
- Scalable: Able to multiplex up to 6,144 samples/sequencing run
Capturing Genomic Insights with ExpressPlex 2.0
Insightful DISCOVERY
– Sequence deeper across repertoires & screening campaigns to capture rare, high-value clones
FASTER DESIGN–BUILD–TEST-LEARN CYCLES
– Accelerate affinity maturation, developability, and candidate refinement
BETTER DECISIONS
– Rich genomic datasets at every stage of of the pipeline for higher confidence
EARLIER RISK REDUCTION
– Screen larger panels for liabilities for improved downstream success rates
SCALABLE DATA FOR AI LEARNING
– Unlock larger sequence–function datasets to power predictive modeling and next-gen engineering
ExpressPlex Workflow
RECORDED WEBINAR
Moderna presentation – Antibody Sequencing: New Operating Model
In this presentation, Nasthas Lacerda Almeida from Moderna, highlights how her organization has leveraged ExpressPlex™ 2.0 for a clonal antibody sequencing approach, optimized for speed and scalability using de novo assembly of NGS short reads.
Hidden Savings. Clear Value.
How is this possible?
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65% faster workflow
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> 90% labor savings
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> 90% consumables saving
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Massive multiplexing
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Indexes & purification beads included in kit
Don’t let library prep be your bottleneck
Harness ExpressPlex miniaturization, multiplexing, and automation compatibility to turn your benchtop sequencer into a cost-effective sequencing factory. Streamline your end-to-end workflow further by eliminating plasmid purification using colony PCR or rolling circle amplification (RCA).
• Colony-to-sequence data in <24 hours
• Up to 6144 unique indexes
• 96-, 384- and bulk reagent formats available
The Biomek Echo One High-Throughput Genomics Workstation and seqWell’s ExpressPlex™ 2.0 Enable Miniaturized, Fully Automated NGS Library Preparation for Ultra High Throughput Sequencing
Blogs of Interest
