Scalable Genotyping-by-Sequencing for Agrigenomics
Simplified workflows. Population-scale sequencing. Better, faster decisions.
seqWell scalable library prep solutions bred for plant, animal & aquaculture-based agrigenomics.
The Shift is Here.
Sequencing is redefining agrigenomics—but complexity, throughput, and cost have slowed its impact. seqWell removes those barriers with simple, transposase-based workflows that make genome-wide data practical at population scale. From variant discovery and trait mapping, to parentage analysis, genomic selection, and crop & livestock improvement – seqWell’s library prep portfolio powers today’s high-throughput sequencing applications for tomorrow’s agrigenomic breakthroughs.
Streamlined Workflows Engineered for Real-world Agrigenomic Programs
SCALABLE GENOtyping
Pilot studies to population-scale programs
Rapid, automation-friendly workflows
Massive multiplexing
FLEXIBle
Crops, livestock & aquaculture
Hybrid capture, low-pass WGS and high-depth coverage
EFFICIENT
Improved laboratory productivity
Reduced sequencing cost per sample
Future-proof data
Library Prep for Short- & Long-Read Low-Pass WGS and Hybrid Capture Workflows
- AgriPrep Library Prep Kit – propelling population-scale, low-pass WGS and SKIM-seq applications using an affordable, 100-minute, one-step library prep workflow for highly multiplexed short-read NGS
- LongPlex Multiplexing Kit – combining high-throughput fragmentation & multiplexing with long-read hybrid capture or low pass WGS applications to unlock discovery and genotyping of simple and complex variants
- MosaiX – scalable library prep with indexing flexibility based on seqWell directional TnX tagmentation for high-performance libraries supporting hybrid capture or WGS applications
Short Reads or Long Reads? How Sequencing Strategy Shapes Trait Mapping and Genotyping-by-Sequencing
Arrays are fixed. Breeding isn’t.
Beyond Arrays – the Blended Approach
Move beyond fixed marker panels with flexible sequencing workflows that combine genome-wide discovery and targeted precision—at population scale. Modern breeding requires insight across diverse and evolving populations, detection of rare and emerging variants, and the flexibility to monitor the continually changing landscape of loci with economic impacts.
Targeted sequencing or hybrid capture → high-confidence calls at critical loci
Low-pass WGS (lpWGS) → genome-wide variation and discovery
A blended sequencing strategy replaces fixed panels with a dynamic, future-ready approach—expanding what you can see, and what you can decide. Together, the blended approach allows you to evolve without starting over.
- Extend legacy datasets without redesigning arrays
- Increases usable genetic information per sample
- Adapt as populations, traits, and references evolve
Beyond Arrays: How a Blended Low Pass + Targeted GBS Strategy Is Reshaping AgBio Genotyping
MICROARRAY CONVERSION: AgriPrep library prep made conversion of microarray-based mouse genotyping to lpWGS a reality for the JAX Genome Technologies Laboratory at The Jackson Laboratory.
Single-Step Library Preparation Workflow Enables High-Throughput Low-Pass Whole-Genome Sequencing Without Compromising Accuracy
Posters of Interest
AgriPrep – Center for Aquaculture Technologies
High Throughput Low Pass Whole Genome Sequencing for Genomics Applications in Aquaculture
LongPlex – HudsonAlpha Institute for Biotechnology
Long-Read Low-Pass Sequencing: A Scalable Strategy for High-Resolution Genotyping