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Normalizing UDI Library Construction Poster Summary

Most available unique dual indexing (UDI) methods incorporate indexing into the library PCR step, which can be labor and cost intensive. In this poster, we describe a novel approach for an auto-normalizing UDI library construction that permits pooling of samples immediately after sequential transposes mediated tagging steps.

Discover true multiplexing with plexWell technology

  • Simplify your workflow by multiplexing up to 2,304 samples without the need for automation.
  • Skip time consuming normalization steps with built-in auto-normalization.
  • Save money and reduce waste with fewer tips required.


  • Whole microbial and metagenomic sequencing
  • Plasmids and PCR amplicons
  • Low pass WGS
  • SARS-CoV-2 sequencing/li>
  • Single cell RNA-seq

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True multiplexing > Built-in normalization > Simplify library prep with plexWell

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seqWell’s workflow and reagent engineering approach helps researchers harness the capacity of modern sequencing instruments to accelerate their research at scale.

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Enabling Sequencing Applications with Improved Transposase-Based SolutionsUPCOMING WEBINAR

Date:  October 19, 2022
Time: 12:00pm (PDT),  3:00pm (EDT), 9:00pm (CEDT)

Learning Objectives

  • Understand the utility of Tn5 transposase and tagmentation across a range of NGS applications
  • Recognize how transposase-based library prep methods permit significant improvements in sequencing workflows without compromising data quality
  • Identify opportunities for incorporating custom Tn5 transposase solutions that allow new innovations in your lab


Joseph C. Mellor, Ph.D.
Co-founder and Chief Scientific Officer, seqWell

Jessica M. Smith, Ph.D.
Director of Bioinformatics, seqWell

Curtis Knox
Director of Product Management, seqWell