*All times based on processing of 96 samples
Here we demonstrate purePlex’s ability to generate highly multiplexed pools of lcWGS libraries from Cannabis sativa samples using an automation workflow on a Sciclone G3 NGSx Workstation liquid handler for sequencing on an Illumina NovaSeq instrument.
Here we demonstrate how the purePlex DNA Library Prep Kit, paired with the AVITI System, improves the performance of mid-throughput, low-pass WGS at a competitive price point. This combination enables flexible, scalable, and efficient low-pass sequencing and genotyping, including kinship analysis.
Low-pass WGS has transformed genomic analysis by providing cost-effective insights into various biological processes. However, this application can be associated with a high error rate that may offset its advantages over genotyping arrays.
In this blog, we outline common challenges encountered during low-pass WGS, including index hopping and lack of library complexity, and describe how innovations like purePlex help you increase success rates and maintain consistency in your workflow.