Advances in massively parallel sequencing and bioinformatics have enabled the routine use of whole-genome sequencing (WGS) in both research and clinical settings. While most applications require coverage depths in the range of 20X – 100X, low-pass or low-coverage (<1X) WGS is emerging as a powerful technique for detecting genome-wide genetic variation.
Download the Application Note to learn the wide-ranging benefits of high-throughput, low-pass whole-genome sequencing.
Gencove’s imputation SaaS in combination with seqWell’s low pass library preparation kit outperforms genotyping arrays.
Joseph C. Mellor, Ph.D.
Co-founder and Chief Scientific Officer, seqWell
Jessica M. Smith, Ph.D.
Director of Bioinformatics, seqWell
Director of Product Management, seqWell